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Thisimi-logo training project is integrated into  Translocation, a larger European Network within the Innovative Medicine Initiative (IMI) wherein five major pharmaceutical companies defined a number of current bottlenecks in the antibiotic development. In close collaboration with 27 organizations (SME, large companies, universities and research centers) the Translocation consortium is searching for solutions to increase antibiotic concentration inside bacteria.



Within this  ITN project ” Molecular Basis of Antibiotic Translocation  ” we integrated twelve young scientists into the larger target driven project and trained young scientists with a different scientific background to go beyond the classical faculty border. Bridging nanotechnology, physics, chemistry, computer modeling, pharmacology and microbiology together we have facilitated the transfer of expertise acquired within the network in both academia and industry.


The main goal of the Training has been to  prepare young researcher for cross disciplinary tasks.  Our Fellows have achieved a scientific culture of mutual understanding across traditional scientific disciplines. Making the young fellows experts not only in their own field of study but able to understand neighboring disciplines, has been the main goal of the present project.

ragazzi-unitiWe offered combined research in related areas such as clinical microbiology, electrophysiology, X-ray crystallography, molecular modeling, bioinformatics, chemistry and medicinal chemistry, biochemistry, single molecule manipulation, and high-throughput technology.


In detail, during the ITN Marie Sklodowska Curie Translocation Project, our 12 students have received a structured training program which included:

  • Experience in biophysical, biochemical, medicinal chemistry and microbiological methods and techniques.
  • Experience in molecular modeling and bioinformatics incl. high-performance computing at European supercomputer centers. In particular kinetic modeling is just at the beginning and has an important impact in data interpretation.
  • Familiarity with technologies used in the future European research infrastructure.
  • International flexibility: fellows graduating from the network are now used to work in an international environment, which will increase their flexibility in their further careers.
  • International networking in research and education: the network meetings and schools provided an opportunity for networking with scientists at the European and international level, broadening the fellow’s understanding of the European academic job market. Through their secondments, fellows received an understanding of the requirements of several different educational systems. This experience has helped fellows to tailor their applications to the needs of the different systems.