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Nr Authors

Title

Journal Year
1 Blondiaux N, Moune M, Desroses M, Frita R, Flipo M, Mathys V, Soetaert K, Kiass M, Delorme V, Djaout K, Trebosc V, Kemmer C, Wintjens R, Wohlkönig A, Antoine R, Huot L, Hot D, Coscolla M, Feldmann J, Gagneux S, Locht C, Brodin P, Gitzinger M, Déprez B, Willand N, Baulard AR.

Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420.

Science. 2017 Mar 17;355(6330):1206-1211

doi: 10.1126/science.aag1006. Epub 2017 Mar 16.

2017
2 Harsha Bajaj,Silvia Acosta Gutierrez, Igor Bodrenko, Giuliano Malloci, Mariano Andrea Scorciapino, Mathias Winterhalter, Matteo Ceccarelli Bacterial Outer Membrane Porins as

Electrostatic Nanosieves: Exploring Transport

Rules of Small Polar Molecules

ACS Nano 2017, 11, 4598−4606

doiI: 10.1021/acsnano.6b08613

2017
3 Mariano Andrea Scorciapino, Silvia Acosta-Gutierrez, Dehbia Benkerrou,Tommaso D’Agostino, Giuliano Malloci, Susruta Samanta, Igor Bodrenko and Matteo Ceccarelli Rationalizing the permeation of polar antibiotics into Gram-negative bacteria Journal of Physics: Condensed Matter, Volume 29, Number 11

doiI: 10.1088/1361-648X/aa543b

2017
4 Glenwright AJ, Pothula KR, Bhamidimarri SP, Chorev DS, Baslé A, Firbank SJ, Zheng H, Robinson CV, Winterhalter M, Kleinekathöfer U, Bolam DN, van den Berg B Structural basis for nutrient acquisition by dominant members of the human gut microbiota Nature, in press

doi: 10.1038/nature20828

2017
5 Ramaswamy VK, Cacciotto P, Malloci G, Vargiu AV, Ruggerone P Computational modelling of efflux pumps and their inhibitors Essays in Biochemistry 2017
6 Cacciotto P, Ramaswamy VK, Malloci G, Ruggerone P, Vargiu AV Molecular modeling of multi-drug properties of RND transporters in Bacterial Multidrug Exporters, Ed. A Yamaguchi (Springer Verlag, Heidelberg, New York) 2017
7 Ferrara LG, Wallat GD, Moynié L, Dhanasekar NN, Aliouane S, Acosta-Gutiérrez S, Pagès JM, Bolla JM, Winterhalter M, Ceccarelli M, Naismith JH MOMP from Campylobacter jejuni Is a Trimer of 18-Stranded β-Barrel Monomers with a Ca2+ Ion Bound at the Constriction Zone. J Mol Biol 428(22): 4528-4543

doi: 10.1016/j.jmb.2016.09.021.

2016
8 Göpfrich K, Li CY, Ricci M, Bhamidimarri SP, Yoo J, Gyenes B, Ohmann A, Winterhalter M, Aksimentiev A, Keyser UF Large-Conductance Transmembrane Porin Made from DNA Origami ACS Nano 10(9): 8207-14

doi: 10.1021/acsnano.6b03759

2016
9 Göpfrich K, Li CY, Mames I, Bhamidimarri SP, Ricci M, Yoo J, Mames A, Ohmann A, Winterhalter M, Stulz E, Aksimentiev A, Keyser UF Ion Channels Made from a Single Membrane-Spanning DNA Duplex Nano Lett 16(7): 4665-9

doi: 10.1021/acs.nanolett.6b02039

2016
10 Trebosc V, Gartenmann S, Royet K, Manfredi P, Tötzl M, Schellhorn B, Pieren M, Tigges M, Lociuro S, Sennhenn PC, Gitzinger M, Bumann D, Kemmer C A novel genome editing platform for drug resistant Acinetobacter baumannii revealed an AdeR-unrelated tigecycline resistance mechanism Antimicrob Agents Chemother 60(12): 7263-7271

doi: 10.1128/AAC.01275-16

2016
11 Arunmanee W, Pathania M, Solovyova AS, Le Brun AP, Ridley H, Baslé A, van den Berg B, Lakey JH Gram-negative trimeric porins have specific LPS binding sites that are essential for porin biogenesis. Proc Natl Acad Sci USA 113(34): E5034-43

doi: 10.1073/pnas.1602382113

2016
12 Bhamidimarri SP, Prajapati JD, van den Berg B, Winterhalter M, Kleinekathöfer U Role of Electroosmosis in the Permeation of Neutral Molecules: CymA and Cyclodextrin as an Example Biophys J 110(3): 600-11

doi: 10.1016/j.bpj.2015.12.027

2016
13 Zahn M, Bhamidimarri SP, Baslé A, Winterhalter M, van den Berg B. Structural Insights into Outer Membrane Permeability of Acinetobacter baumannii. Structure 24(2): 221-31

doi: 10.1016/j.str.2015.12.009

2016
14 Scorciapino MA, D’Agostino T, Acosta-Gutierrez S, Malloci G, Bodrenko I, Ceccarelli M Exploiting the porin pathway for polar compound delivery into Gram-negative bacteria. Future Med Chem 8(10): 1047-62

doi: 10.4155/fmc-2016-0038

2016
15 Acosta Gutiérrez S, Bodrenko I, Scorciapino MA, Ceccarelli M Macroscopic electric field inside water-filled biological nanopores Phys Chem Chem Phys 18(13): 8855-64.

doi: 10.1039/c5cp07902k

2016
16 Ramaswamy VK, Cacciotto P, Malloci G, Ruggerone P, Vargiu AV Multidrug efflux pumps and their inhibitors characterized by computational modeling in Efflux-Mediated Drug Resistance in Bacteria: Mechanisms, Regulation and Clinical Implications, Eds. X-Z Li, CA Elkins, HI Zgurskaya (Springer Verlag, Heidelberg, New York): 797-831.

doi: 10.1007/978-3-319-39658-3_30

2016
17 Kovácsová G, Gustavsson E, Wang J, Kreir M, Peuker S, Westenhoff S Cell-free expression of a functional pore-only sodium channel Protein Expr Purif 111: 42-7

doi: 10.1016/j.pep.2015.03.002

2015
18 van den Berg B, Bhamidimarri SP, Dahyabhai Prajapati J, Kleinekathöfer U, Winterhalter M Outer-membrane translocation of bulky small molecules by passive diffusion Proc Natl Acad Sci USA 112 (23): E2991-9

doi: 10.1073/pnas.1424835112

2015
19 Acosta-Gutierrez S, Scorciapino M, Mariano A, Bodrenko I, et al. Filtering with Electric Field: The Case of E. coli Porins J Phys Chem Lett 6:1807-1812

doi: 10.1021/acs.jpclett.5b00612

2015
20 Van den Berg B, Bhamidimarri SP, Winterhalter M Crystal structure of a COG4313 outer membrane channel Sci Report 5: 11927

doi:10.1038/srep11927

2015
21 Blair JM, Bavro VN, Ricci V, Modi N, Cacciotto P, Kleinekathӧfer U, Ruggerone P, Vargiu AV, Baylay AJ, Smith HE, Brandon Y, Galloway D, Piddock LJ AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity Proc Natl Acad Sci USA 112(11): 3511-6

doi: 10.1073/pnas.1419939112

2015
22 Klingler FM, Wichelhaus TA, Frank D, Cuesta-Bernal J, El-Delik J, Müller HF, Sjuts H, Göttig S, Koenigs A, Pos KM, Pogoryelov D, Proschak E Approved Drugs Containing Thiols as Inhibitors of Metallo-β-lactamases: Strategy To Combat Multidrug-Resistant Bacteria J Med Chem 58(8): 3626-30

doi: 10.1021/jm501844d.

Erratum in: J Med Chem 58(15): 6320

2015
23 Weichbrodt C, Bajaj H, Baaken G, Wang J, Guinot S, Kreir M, Behrends JC, Winterhalter M, Fertig N Antibiotic translocation through porins studied in planar lipid bilayers using parallel platforms Analyst 140(14): 4874-81

doi: 10.1039/c4an02335h

2015