Born on December 30, 1988 in Bangalore, India, Venkata Krishnan Ramaswamy graduated in Pharmacy from The Tamil Nadu Dr. M.G.R. Medical University in 2010 and specialized in Pharmacoinformatics from National Institute of Pharmaceutical Education and Research (NIPER), Mohali in 2013. He then worked as a senior research fellow on an Open Source-Cheminformatics project during 2013/2014 and made significant contribution towards the development of MPDS (Molecular Property Diagnostic Suite), a software toolset that rationally diagnoses molecules to aid drug discovery science.
Currently, he is a Marie Skłodowska-Curie Fellow within the framework of the ITN Translocation project and is enrolled as a PhD student in the department of Physics at the University of Cagliari, Italy. His doctoral research focuses on characterizing the structural and dynamic similarities and differences of the substrate recognition and transport pathways, arising from an underlying difference in their amino acid composition, among the principal RND transporter proteins in E. coli and P. aeruginosa.
Venkata Krishnan Ramaswamy says: “Winning this prestigious fellowship was a life-changing opportunity especially because of the large collaborative network involving eminent scientists from academia and industries enabling a highly rewarding knowledge exchange“.
ITN Project: Key residues in RND transporter
- Ramaswamy, V. K., Vargiu, A.V., Malloci, G., Dreier, J. G., & Ruggerone, P.”Molecular rationale behind the differential substrate specificity of bacterial RND multi-drug transporters”. Scientific reports, 7(1), 8075.
Cacciotto, P., Ramaswamy, V. K., Malloci, G., Ruggerone, P., & Vargiu, A. V. “Molecular modeling of multi-drug properties of RND transporters”. Bacterial Multidrug Exporters of the series Methods in Molecular Biology, Ed. Yamaguchi A. (Springer Verlag, Heidelberg, New York, 2017) (In Press)
Ramaswamy, V. K., Cacciotto, P., Malloci, G., Ruggerone, P., & Vargiu, A. V. “Multidrug efflux pumps and their inhibitors characterized by computational modeling”. X.-Z. Li et al. (eds.), in Efflux-Mediated Drug Resistance in Bacteria (Springer Verlag, Heidelberg, New York, 2016): 797-831. (DOI 10.1007/978-3-319-39658-3_30)
Ramaswamy, V.K., Cacciotto P, Malloci G, Vargiu AV, Ruggerone P. “Computational modeling of efflux pumps and their inhibitors”. Essays in Biochemistry, 61(1) 141-156.