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Silvia Acosta Gutiérrez


Silvia Acosta Gutiérrez  was born in Tenerife, Spain in 1987. She graduated at University of La Laguna, Tenerife, Spain and earned a Bachelor degree in Physics. Before starting her Master she started doing research in the field of Atomic and Molecular Physics, carrying a study in small water clusters under low and moderate electric fields. In September 2011, she completed her Master’s degree in ‘Physics: Structure of Matter and Computational Sciences’ at the same university. She wrote her dissertation in the field of Computational Molecular physics with the title of ‘Optimal covering of C60 by rare gases’. The project was completed by carrying out an intensive research in global optimization of energy landscapes by using ‘Basin-hopping’ Monte Carlo based techniques.

Currently she is a  Marie Skłodowska-Curie Fellow within the ITN Translocation project and is enrolled in a PhD program in the Department of Physics at the University of Cagliari in Italy. Her research focuses on the development of computational models for evaluating outer membrane permeability.

ITN-Translocation has been a great opportunity to develop as a scientist. It has provided me with a broad vision of “what to be a researcher means”, from lab work to networking and management. Being part of a multidisciplinary network has challenged myself to integrate my work and skills in a synergistic way with others’ work, and most importantly to find a common language to explain my research to scientists with a very different background.

Recipient of International Travel Award to the 60th Annual Meeting of the Biophysical Society. Press Released 4 Dec 2015


Contact: silvia.acosta@dsf.unica.it

Personal webpage: http://sacosta-gutierrez.weebly.com

ITN Project: Pathaway modeling 


  • Harsha Bajaj, Silvia Acosta-Gutiérrez, Igor Bodrenko, Giuliano Malloci, Mariano Andrea Scorciapino, Mathias Winterhalter and Matteo Ceccarelli. “Bacterial Outer Membrane Porins as Electrostatic Nanosieves: exploring transport rules of small polar molecules”. ACS Nano 2017, 11, 4598-4606.
  • Mariano Andrea Scorciapino, Silvia Acosta-Gutiérrez, Dehbia Benkerrou, Tommaso D’Agostino, Giuliano Malloci, Susruta Samanta, Igor Bodrenko and Matteo Ceccarelli. “Rationalizing the permeation of polar antibiotics into Gram-negative bacteria.” Journal of Phyics: Condensed Matter, Volume 29, Number 11 (2017).
  • Luana G M Ferrara, Gregor D Wallat, Lucile Moynié, Naresh N Dhanasekar, Soumeya Aliouane, Silvia Acosta-Gutiérrez, Jean-Marie Pagés, Jean-Michel Bolla, Mathias Winterhalter, Matteo Ceccarelli, James H Naismith. “MOMP from Campylobacter jejuni is a trimer of 18 stranded β-barrel monomers with a Ca2+ ion bound at the constriction zone”. J. Mol. Biol. (2016)

  • Mariano Andrea Scorciapino, Tommaso D’Agostino, Silvia Acosta-Gutiérrez, Giuliano Malloci, Igor Bodrenko and Matteo Ceccarelli. “Exploiting the porin pathway for polar compound delivery into Gram-negative bacteria”. Future Medicinal Chemistry, 8 1047-1062 (2016).

  • Silvia Acosta-Gutiérrez, Igor Bodrenko, Mariano Andrea Scorciapino and Matteo Ceccarelli. “Macroscopic electric field inside water-filled biological nanopores”. Phys.Chem.Chem.Phys ,18 8855-8864 (2016).

  • Silvia Acosta-Gutiérrez, Mariano Andrea Scorciapino, Igor Bodrenko, and Matteo Ceccarelli. “Filtering with Electric Field: The Case of E. coli Porins”. Journal of Physical Chemistry Letters, 61807-1812 (2015).